From the source rules
Who goes first in Trismegistus?
English Board&Dice New Edition multiplayer rules

Whoever made a potion most recently starts.
Rule details
Put that player's marker first on the turn-order track, then place the other players' markers clockwise.
This is the revised New Edition. The original game, The Ultimate Formula, has a separate entry with different setup instructions.
The setup does not define what counts as a potion. This entry covers the multiplayer manual, not the separately offered solo rules.
Source & edition
- Trismegistus: Board&Dice rulesBoard&Dice · Cover; Player Setup, steps A and C3 · Checked 2026-09-23Printed page references: 8Cited PDF pages: 1, 8
Image: © Board&Dice (publisher) · Board&Dice
If there’s a tie
The rulebook doesn’t say.
Related games and editions
Browse available game rulesGames with a similar starting rule
Die Zausel vom ZauberwaldThe player who most recently stumbled starts.
Into the BlueThe player who swam most recently starts the game.
CanvasWhoever painted most recently goes first.
IwariWhoever traveled most recently takes the first turn.
SeptimaIn multiplayer, whoever most recently made a mixed drink is the starting player.
Free game-night tools: score keeper · turn timer · dice roller · all tools
Found a different instruction in your edition? Send a correction with the game, edition, and source.